BowieRecruiter Since 2001
the smart solution for Bowie jobs

Associate Scientist/Eng. I/II - Downstream Process Development

Company: Paragon Gene Therapy, a unit of Catalent Biologics
Location: Baltimore
Posted on: August 21, 2019

Job Description:

Paragon Gene Therapy, now a part of Catalent, hires people with a passion to make a difference. Your expertise, coupled with our advanced technologies and collaboration with innovative pharmaceutical, biotech and healthcare companies, will help bring life-enhancing products to the people you know and love. Your talents, ideas and passion are essential to our mission; to develop, manufacture and supply products that help people live better, healthier lives. Paragon Gene Therapy, in Baltimore & Harmans, Maryland, provides industry-leading GMP development and manufacturing services for cutting-edge biopharmaceuticals such as recombinant viral vectors, next generation vaccines & hard-to-express recombinant proteins and oncolytic viruses. The Associate Scientist/Engineer I/II is actively engaged in process and product development within a dynamic team and displays strong technical knowledge, initiative, and scientific commitment, and makes significant scientific and technical contributions to downstream process development.Key Responsibilities Include, but are not limited to:

  • Integral team member in moving projects forward toward GMP Manufacturing for clinical trials, registration, improvements of existing processes and products
  • Participates in decision-making processes within the project team by actively engaging in scientific and technical discussions
  • Performs work encompassing different projects and programs including:
    • Downstream process development of recombinant protein, virus-like particle, and virus purification processes
    • Primary recovery from cell paste or inclusion bodies of specific proteins/macromolecules
    • Downstream processing of macromolecules expressed in mammalian cell lines, insect cells, or microbes
    • Development and execution of purification and analytical protocols
    • Interaction with appropriate members of upstream and analytical functional areas for purification and analysis of target molecules
    • Interaction with appropriate members of quality for review of documentation
    • Deploys knowledge and technical skills to independently design and execute studies
    • Builds credibility within group by performing high quality work
    • Expands the technical capabilities of Process Development group, by offering expertise in areas such as technology development, platform or systems development, or using a literature precedent
    • Teaches others in their area of expertise, and assists with work being performed by other members of the Downstream Process Development group
    • Documents and effectively communicates results of individual executed work through summary presentations, discussions with supervisor, and scientific meetings on a regular basis.
    • Possesses considerable knowledge and expertise relating to protein purification and analysis and other fundamental lab technologies or platforms Education & Experience:
      • AS I - Bachelor of Science in a life science or chemical engineering field plus 0-3 years experience
      • AS or Eng II - M.S. in a life science or chemical engineering field plus 0-3 years experience OR B.S. in a life science or chemical engineering field plus 3-5 years experience with chromatography based processing methods such as Affinity, Ion Exchange, Hydrophobic Interaction, and Size Exclusion is required as is column packing.
      • Analytical techniques: Gel Electrophoresis (SDS PAGE Gel), Western Blotting, HPLC, Bioactivity assays, Colorimetric Protein assays, and Spectroscopic Measurements required
      • Knowledge of how GMP regulations impact process development of biologics products
      • Demonstrated familiarity with AKTA chromatography systems and UNICORN software is strongly desired
      • Familiarity with instrument care, maintenance, troubleshooting, and data interpretation
      • Experience with filtration processing using Crossflow or Tangential Flow Filtration techniques is a plus
      • Understanding of protein biochemistry (protein folding, protein degradation, aggregation, etc.
      • Ease with document writing, data interpretation, presentation skills, and statistical analysis
      • The ability to work in team oriented environment is essential, as this person will work closely with other members of Process Development Group, QC, GMP, and participate on multidisciplinary project teams
      • Previous experience working in Biotechnology or Pharmaceutical industry considered a plus. Paragon Bioservices is proud to be an Equal Employment Opportunity and Affirmative Action employer. We do not discriminate based upon race, religion, color, national origin, gender (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, gender expression, age, status as a protected veteran, status as an individual with a disability, or other applicable legally protected characteristics. #LI-EW1

Keywords: Paragon Gene Therapy, a unit of Catalent Biologics, Bowie , Associate Scientist/Eng. I/II - Downstream Process Development, Engineering , Baltimore, Maryland

Click here to apply!

Didn't find what you're looking for? Search again!

I'm looking for
in category
within


Other Engineering Jobs


RF Microwave Design Engineer with Security Clearance
Description: Description Northrop Grumman Missions Systems is seeking experienced engineers in the following areas: Antennas, Electromagnetics, Computational Electromagnetics, RF/Microwave design, Digital beam-forming, (more...)
Company: Acro Service Corp.
Location: Baltimore
Posted on: 09/16/2019

Mechanic
Description: Join Our Team Sunbelt Rentals strives to be the customer's first choice in the equipment rental industry. From pumps to scaffolding to general construction tools, we aim to be the only call needed to (more...)
Company: Sunbelt Rentals, Inc.
Location: Gaithersburg
Posted on: 09/16/2019

Solutions Engineer with Security Clearance
Description: Raven Aerostar is a world leader in lighter-than-air, stratospheric, and situational awareness technology. Committed to rapid innovation of highly technical and groundbreaking technology, we design and (more...)
Company: Raven Industries Inc
Location: Arlington
Posted on: 09/16/2019


Hotel Engineer Tech - Orlando, FL Region - Marriott International HQ - (19079734)
Description: Here's To Your Journey with Marriott Hotels Resorts Suites Marriott International is the world's largest hotel company, with more brands, more hotels and more opportunities for associates to grow and (more...)
Company: Marriott International, Inc.
Location: Bethesda
Posted on: 09/16/2019

HVAC Service Technician
Description: Join our growing service team Compu Dynamics has an immediate opening for a Journeyman Service Technician covering the DC Metro area. 500 sign on bonus br br Essential Functions: br Reasonable (more...)
Company: COMPU DYNAMICS LLC
Location: Lanham
Posted on: 09/16/2019

Principal Field Engineer - SIGINT with Security Clearance
Description: Technical Specialists provide close-access technical SIGINT collection in support of customer operations around the globe. As a member of a highly elite team of personnel you will be performing both ground (more...)
Company: Raytheon
Location: Fairfax
Posted on: 09/16/2019

Cloud Engineer, Mid with Security Clearance
Description: Job Number: R0062601 Cloud Engineer, Mid br The Challenge: We have the te chn ology, but do we know how to us e it In an ind us try where cloud is sometimes synonymo us with genie, it's important (more...)
Company: Booz Allen Hamilton
Location: Arlington
Posted on: 09/16/2019

Mr. Tire - Automotive Technician
Description: Job DescriptionAutomotive technicians, are you tired of that dead end job and want a career with our winning team that provides unlimited opportunities and earning potential Every technician as to do (more...)
Company: Mr. Tire Auto Service Centers
Location: Falls Church
Posted on: 09/16/2019

Platform Engineer with Security Clearance
Description: Cyberspace Solutions CSS is a prime provider of full spectrum, on-site CONUS/theater , intelligence, special operations, cyber, analytics, technical and operations support services. We also provide (more...)
Company: Cyberspace Solutions
Location: Springfield
Posted on: 09/16/2019

Test Engineer with Security Clearance
Description: Title: Test Engineer Location: McLean, Virginia Clearance: TS/SCI w/ Polygraph Company Overview: Cornerstone Defense, in partnership with our military, intelligence, and civil government customers, supports (more...)
Company: Cornerstone Defense
Location: Fairfax
Posted on: 09/16/2019

Log In or Create An Account

Get the latest Maryland jobs by following @recnetMD on Twitter!

Bowie RSS job feeds